منابع مشابه
Host Defense against Bacterial Endotoxemia: Mechanism in Normal Animals
The present study defines the early response of normal rabbits to the intravenous injection of a single, sublethal dose of endotoxin. Within the first few hours following endotoxin there occurs in the circulating plasma of recipients a decrease in ionized calcium, a threefold increase in the heat-stable, organo-phosphate-resistant esterase level, and a striking increase in the endotoxin-detoxif...
متن کاملThe Journal of Nutrition Symposium: Micronutrient Regulation of Host-Pathogen Interactions Zinc: Mechanisms of Host Defense
Zinc deficiency in humans decreases the activity of serum thymulin (a thymic hormone), which is required for maturation of T-helper cells. T-helper 1 (Th1) cytokines are decreased but T-helper 2 (Th2) cytokines are not affected by zinc deficiency in humans. This shift of Th1 to Th2 function results in cell-mediated immune dysfunction. Because IL-2 production (Th1 cytokine) is decreased, this le...
متن کاملHost Defense Mechanism-Based Rational Design of Live Vaccine
Live attenuated vaccine (LAV), mimicking natural infection, provides an excellent protection against microbial infection. The development of LAV, however, still remains highly empirical and the rational design of clinically useful LAV is scarcely available. Apoptosis and caspase activation are general host antiviral responses in virus-infected cells. Utilizing these tightly regulated host defen...
متن کاملTranscript analysis of some defense genes of tomato in response to host and non-host bacterial pathogens
The transcript levels of six defense genes including pathogenesis-related gene 1 (PR-1), pathogenesis-related gene 2 (PR-2), pathogenesis-related gene 5 (PR-5), lipoxygenase (LOX), phenylalanine ammonia-lyase (PAL) and catalase (CAT) were investigated in tomato plants inoculated with Xanthomonas axonopodis pv. phaseoli as a non-host pathogen and X. euvesicatoria as a host pathogen. Activation o...
متن کاملCollectins and pulmonary host defense.
The surfactant-associated proteins SP-A and SP-D are members of a family of collagenous host defense lectins, designated collectins. There is increasing evidence that these pulmonary epithelial-derived proteins are important components of the innate immune response to microbial challenge, and that they participate in other aspects of immune and inflammatory regulation within the lung. The colle...
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ژورنال
عنوان ژورنال: The Japanese Journal of Nutrition and Dietetics
سال: 1984
ISSN: 1883-7921,0021-5147
DOI: 10.5264/eiyogakuzashi.42.3